Is 200 Proof Food-Grade Alcohol Really the Best Solvent? Here Is What the Evidence Suggests
The answer that experienced extractors give to this question is almost always "it depends," and that is not evasion. It is the correct answer. Choosing the best solvent for making extractions is not a question with a single response. It is a function of what compounds you are targeting, what plant or fungal material you are working with, and what the finished product needs to do. 200 proof food grade alcohol is 100% ethanol. No water. No other components. That anhydrous quality makes it exceptionally effective at dissolving fat-soluble compounds, including resins, essential oils, and the triterpenes found in medicinal mushrooms. It also evaporates completely, leaving no solvent residue in the finished extract. But not everything you want from a botanical extraction is fat-soluble. Beta-glucans and polysaccharides, which are among the most studied compounds in medicinal mushrooms for immune support, are water-soluble. Pure 200-proof ethanol would pull the fat-soluble...